E Mesothelioma Treatment

Multaq Warning : Liver cancer is not only curable, it is often preventable. Lifestyle choices contribute to the likelihood that an individual will contract HCC. As you can see from die following list, most of the strategies for avoiding liver cancer involve not putting yourself at risk.’

* Never, ever smoke. Did you need another reason to quit smoking tobacco?

• Limit your drinking. Alcohol damages the liver. Alcohol abuse can cause cirrhosis, so why take the risk of drinking if your liver is healthy? If you have a liver disorder, too much alcohol will accelerate the disease.
• Exercise and maintain a healthy weight. Obesity and insulin resistance cause nonalcoholic fatty liver disease and contribute to other liver disorders. Keep your liver healthy with a heart-healthy diet and regular exercise.
• Avoid exposure to hepatitis B (HBV) and hepatitis C (HCV). People who engage in unprotected sex or share intravenous needles (including those used in giving tat­toos), or who live with an HBV or HCV patient, are at risk for contracting those diseases. Never share needles or have unprotected sex.
• If you are at risk for hepatitis B, take the HBV vac­cination. Family members of patients with HBV should be vaccinated so they are protected from contracting the disease. Currently, it is recommended that all infants in the United States receive the hepatitis B vaccine series.
• Never take anabolic steroids. These steroids have made headlines because professional athletes have admitted to taking them. Anabolic steroids may cause cancer.
• Learn about aflatoxins. Aflatoxins are cancer-causing toxins produced by a mold. They grow on the skins of corn, peanuts, rice, potatoes, and other such foods. The United States tests for aflatoxins, but it is a good idea to buy foods grown in your own region, rather than those transported from hot, humid locales where molds can grow on stored food.

Liver tumors share many symptoms with other illnesses, so a pri­mary liver cancer can closely resemble other afflictions. Of che liver cancers that can be mistaken for another disorder, a metastatic liver tumor, a cancer that began in some other organ and spread to the liver, is the most serious. Metastatic liver tumors often begin in the colon, kidney, uterus, lungs, stomach, gallblad­der, breast, esophagus, or pancreas, and are more common than primary liver cancers.

Another liver condition that can be mistaken for primary liver cancer is a pseudo tumor. Made of regenerating cirrhosis nod­ules, the pseudotumor nodules often cluster and may resemble a tumor mass. Also capable of fooling imaging equipment is a focal fatty infil­tration of the liver, or fat deposits that are clumped together and resemble a tumor. Obesity, alcoholic liver disease, and diabetes are all potential causes; when the underlying condition is corrected, the fat deposits may disappear.

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The alpha-fetoprotein (AFP) blood test can also mislead patients and doctors. Often used as a tumor marker, this test can detect but not diagnose HCC with elevated blood levels. But a higher-than-normal AFP result can also indicate pregnancy, cystic fibrosis, gastric cancer, pancreatic cancer, metastatic liver cancer (as opposed ro HCC, in which the liver is the primary organ where the cancer originated), or cirrhosis.

With all liver disorders-—-but especially when a cancerous tumor is suspected—patients should remember that making pre­mature assumptions can be hazardous to their health! The best path to a positive long-term prognosis is a series of diagnostic procedures, rather than conclusions drawn from one blood test. This is especially true because of the many symptoms—including jaundice, unexplained weight loss, diminished appetite, and abdominal pain, among others—that may signal HCC or a pre- cancerous condition. It is no longer true that a diagnosis of liver cancer means that the patient is doomed; HCC, if detected early, is now considered one of the curable cancers. But to ensure a successful outcome, it must be detected and treated early.

A scar is usually good news because it indicates that repair and healing following an injury have begun. It is ironic, there­fore, that in the case of cirrhosis, advanced scarring means that the liver is beyond repair. Scarring is perhaps the most serious consequence of liver diseases, although with the advances of modern medicine, cirrhosis isn’t the signal of doom that it once was.

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As cirrhosis develops, scarred tissue replaces the healthy liver. Blood can no longer flow freely through the liver, and as the organ becomes hard and lumpy, its function deteriorates. This condition kills about 27,000 people each year, making it the 10th leading cause of death for men and the 12th for women in the United States.

Scientists have known about cirrhosis and its effects for many centuries. In the 4th century b.c., Hippocrates is believed to have said, “In cases of jaundice it is a bad sign when the liver becomes hard.” In 18th-century England, cirrhosis was known as “gin liver” because the disease developed when a surplus of corn crops brought an abundance of gin. Before 1820, French medical researcher René Laënnec named the disease cin-hose, deriving the term from the Greek word kirrhos, meaning “tawny”-—-the orange- tan color of cirrhotic livers.

Lab indicators of cirrhosis include a low platelet count and per­haps moderately elevated aminotransferases (AST and ALT), with AST levels that are higher than the levels of ALT. Alkaline phos­phatase (AP) will often be slightly elevated, as will the (gamma- glutamyl transpeptidase (GGTP). As the cirrhosis progresses, bilirubin levels may elevate and prothrombin time may increase, as will globulins, while the serum albumin level may fall. Because the liver plays a major role in blood coagulation, that process will be less efficient as the cirrhosis progresses, a change indicated by prolonged prothrombin time and low platelets.

The doctor may also order an ultrasound. Along with show­ing the altered size and nodular appearance that the liver takes on with advanced cirrhosis, the ultrasound screens for complications such as hepatocellular carcinoma (primary liver cancer) and portal hypertension. A CT scan of the abdomen and an MRI of the liver and bile ducrs may also be ordered.

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